Chicago's location is ideal for air cargo. Chicago is centrally located in the United States and is central in one of the world's largest trading areas: the east-west nexus of Europe and Asia and the north-south nexus of the North American Free Trade Agreement.

The only U.S. gateway with all six major North American railroads provides easy multimodal transfer of goods. In fact, 50 percent of all U.S. rail freight passes through Chicago rail yards. Chicago has excellent interstate highway access and is located within a one-day truck drive of 29 percent of North American consumers and within a two-day ride of 42 percent of consumers.